Prison Architect is a game about creating and managing a prison. You get a plot of land, and slowly build up a secure facility, getting money from the government for storing prisoners, and from grants (quests).
Game Dev Tycoon is an interesting game that puts the player into the shoes of a game developer from the 80's. Re-invent your favourite games, combat piracy, or even embrace it. Its a unique game due to its differing gameplay between the legit and pirated versions.